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Effexor XR



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Medication Information

Effexor is used to treat depression. Effexor is also used to treat generalized anxiety disorder (excessive worrying that is difficult to control) and social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life). Effexor is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain.

How should this medicine be used?

Effexor comes as a tablet or extended-release capsule to take by mouth. The regular capsule is usually taken two or three times a day and should be taken with food. The extended-release capsule is usually taken once daily in the morning or evening with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Effexor exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release capsule whole; do not split, chew, crush, or place it in water. If you cannot swallow the extended-release capsule, it may be carefully opened and the entire contents of the capsule sprinkled on a spoonful of applesauce. Swallow (without chewing) this mixture immediately after preparation and then drink a glass of water to make sure all of the medicine is swallowed.

Continue to take Effexor even if you feel well. Do not stop taking Effexor without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.

Other uses for this medicine Effexor is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking Effexor,

tell your doctor and pharmacist if you are allergic to Effexor or any other drugs.
do not take Effexor if you are taking monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl), and tranylcypromine (Parnate), or have stopped taking them within the past two weeks. If you stop taking Effexor, you should wait at least a week before you start to take an MAO inhibitor.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: amiodarone (Cordarone, Pacerone); antidepressants; chlorpheniramine (Chlor-Trimeton); cimetidine (Tagamet); clomipramine (Anafranil); haloperidol (Haldol); imipramine (Tofranil); indinavir (Crixivan); lithium; medications for anxiety, mental illness, or seizures; medications for migraine such as frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); methadone (Dolophine); quinidine (Quinaglute, Quinidex); risperidone (Risperdal); ritonavir (Norvir); sedatives; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft);sleeping pills;and tranquilizers.
tell your doctor if you or anyone in your family has or has ever had depression, bipolar disorder (mood that changes from depressed to abnormally excited), or mania (frenzied, abnormally excited mood), or if you or anyone in your family has thought about or attempted suicide. Also tell your doctor if you have or have ever had difficulty urinating; elevated intraocular pressure; or liver, kidney, or heart disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Effexor, call your doctor immediately.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Effexor. you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
remember that alcohol can add to the drowsiness caused by this drug.you should know that your mental health may change in unexpected ways, especially at the beginning of your treatment and at any time your dose is increased or decreased. These changes may occur at any time if you have depression or other mental illness, whether or not you are taking Effexor or any other medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling or staying asleep; irritability; aggressive behavior; acting without thinking; severe restlessness; and frenzied, abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.

What should I do if I forget a dose?

If you take several doses per day, take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.

If you take Effexor once a day at bedtime and do not remember to take it until the next morning, skip the missed dose. Do not take a double dose to make up for a missed one.

What side effects can Effexor cause?

Side effects from Effexor are common:
upset stomach
drowsiness
weakness or tiredness
excitement or anxiety
insomnia
nightmares
dry mouth
skin more sensitive to sunlight than usual
changes in appetite or weight
headache

l your doctor if any of these symptoms are severe or do not go away:

constipation
difficulty urinating
frequent urination
blurred vision
changes in sex drive or ability
excessive sweating

If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:

jaw, neck, and back muscle spasms
slow or difficult speech
shuffling walk
persistent fine tremor or inability to sit still
fever
difficulty breathing or swallowing
severe skin rash
yellowing of the skin or eyes
irregular heartbeat

What storage conditions are needed for this medicine?

Keep Effexor in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Effexor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.